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Article

Clinical and analytical relevance of NNRTIs minority mutations on viral failure in HIV-1 infected patients.

Journal of medical virology - 1 Mar 2014

Mohamed Sofiane, Ravet Sophie, Camus Claire, Khiri Hacène, Olive Daniel, Halfon Philippe

Abstract excerpt

The objective of this study was to assess the analytical and clinical relevance of minority variants using a new pyrosequencing (PSQ) assay and to detect minor variants with frequencies below the current 20% clinical setting limit. A PSQ approach for detecting and quantifying mutations was developed for the analysis of 14 codons of the human immunodeficiency virus (HIV) reverse transcriptase (RT) gene below the...

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Share to Anti-HIV Agents
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to HIV Infections

Share to HIV Reverse Transcriptase

Share to Mutation, Missense

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Source

Identifiers

PMID: 24248806
DOI: 10.1002/jmv.23853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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