Article
A single variant sequencing method for sensitive and quantitative detection of HIV-1 minority variants.
Scientific reports - 18 May 2020
Sidhu Gurjit, Schuster Layla, Liu Lin, Tamashiro Ryan, Li Eric, Langaee Taimour, Wagner Richard, Wang Gary P
Abstract excerpt
HIV drug resistance is a major threat to achieving long-term viral suppression in HIV-positive individuals. Drug resistant HIV variants, including minority variants, can compromise response to antiretroviral therapy. Many studies have investigated the clinical relevance of drug resistant minority variants, but the level at which minority variants become clinically relevant remains unclear. A combination of...
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