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Article

Consequences of monocarboxylate transporter 8 deficiency for renal transport and metabolism of thyroid hormones in mice.

Endocrinology - 1 Feb 2010

Trajkovic-Arsic Marija, Visser Theo J, Darras Veerle M, Friesema Edith C H, Schlott Bernhard, Mittag Jens, Bauer Karl, Heuer Heike

Abstract excerpt

Patients carrying inactivating mutations in the gene encoding the thyroid hormone transporting monocarboxylate transporter (MCT)-8 suffer from a severe form of psychomotor retardation and exhibit abnormal serum thyroid hormone levels. The thyroidal phenotype characterized by high-serum T(3) and low-serum T(4) levels is also found in mice mutants deficient in MCT8 although the cause of these abnormalities is still...

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Source

Identifiers

PMID: 19996182
DOI: 10.1210/en.2009-1053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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