Article
Thyroid hormone transporters.
Hormone research - 1 Jan 2007
Visser Theo J
Abstract excerpt
BACKGROUND: Cellular uptake and release of thyroid hormone are mediated by transporters. Among these, monocarboxylate transporter 8 (MCT8) shows particularly high activity towards the active thyroid hormone 3,3',5-triiodothyronine (T(3)). MCT8 is expressed in different tissues, including the brain where it is predominantly localized in neurons. The MCT8 gene is located on the X chromosome. CONCLUSIONS: Mutations...
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