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Article

Identification of new residues involved in intramolecular signal transmission in a prokaryotic transcriptional repressor.

Journal of bacteriology - 1 Feb 2014

Molina-Santiago Carlos, Daddaoua Abdelali, Fillet Sandy, Krell Tino, Morel Bertrand, Duque Estrella, Ramos Juan L

Abstract excerpt

TtgV is a member of the IclR family of transcriptional regulators. This regulator controls its own expression and that of the ttgGHI operon, which encodes an RND efflux pump. TtgV has two domains: a GAF-like domain harboring the effector-binding pocket and a helix-turn-helix (HTH) DNA-binding domain, which are linked by a long extended helix. When TtgV is bound to DNA, a kink at residue 86 in the extended helix...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24244009
DOI: 10.1128/JB.00589-13
PMCID: PMC3911149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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