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Article

Transcriptional control by two interacting regulatory proteins: identification of the PtxS binding site at PtxR.

Nucleic acids research - 1 Dec 2013

Daddaoua Abdelali, Krell Tino, Ramos Juan-Luis

Abstract excerpt

The PtxS and PtxR regulators control the expression of the glucose dehydrogenase genes from the Pgad promoter in Pseudomonas aeruginosa. These regulators bind to their cognate operators, that are separated by ∼50 nt, within the promoter region and interact with each other creating a DNA-loop that prevents RNA polymerase promoter access. Binding of the 2-ketogluconate effector to PtxS caused PtxS/PtxR complex...

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Identifiers

PMID: 24019239
DOI: 10.1093/nar/gkt773
PMCID: PMC3905896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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