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Article

Gene-gene and gene-environment interactions in ulcerative colitis.

Human genetics - 1 May 2014

Wang Ming-Hsi, Fiocchi Claudio, Zhu Xiaofeng, Ripke Stephan, Kamboh M Ilyas, Rebert Nancy, Duerr Richard H, Achkar Jean-Paul

Abstract excerpt

Genome-wide association studies (GWAS) have identified at least 133 ulcerative colitis (UC) associated loci. The role of genetic factors in clinical practice is not clearly defined. The relevance of genetic variants to disease pathogenesis is still uncertain because of not characterized gene-gene and gene-environment interactions. We examined the predictive value of combining the 133 UC risk loci with genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24241240
DOI: 10.1007/s00439-013-1395-z
PMCID: PMC4064459

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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