Article

Epithelial regulatory networks link non-coding genetic variation to clinical heterogeneity in ulcerative colitis

2026-08-04

Abstract excerpt

Ulcerative colitis (UC) is a genetically heterogeneous disease causing chronic intestinal inflammation. Genome-wide association studies have linked numerous non-coding single nucleotide polymorphisms (SNPs) to UC, yet how these variants relate to intestinal epithelial function and clinical outcomes remains largely unknown. To address this, we aimed to reconstruct patient-specific epithelial signalling and regulato...

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Literature Corpus work: bd32220a-0cba-5317-a0da-6a6e5e0f0071
DOI: 10.64898/2026.08.04.742507

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