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Article

Efficient method of genotyping ob/ob mice using high resolution melting analysis.

PloS one - 1 Jan 2013

Sutter Alton G, Palanisamy Arun P, Kurtz Nichole, Spyropoulos Demetri D, Chavin Kenneth D

Abstract excerpt

OBJECTIVE: Direct health care costs of obesity continue to grow throughout the world and research on obesity disease models are on the rise. The ob/ob mouse is a well-characterized model of obesity and associated risk factors. Successful breeding and backcrossing onto different backgrounds are essential to create knockout models. Ob/ob mice are sterile and heterozygotes must be identified by genotyping to...

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Identifiers

PMID: 24236058
DOI: 10.1371/journal.pone.0078840
PMCID: PMC3827293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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