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Article

Comparative‑high resolution melting: a novel method of simultaneous screening for small mutations and copy number variations.

Human genetics - 1 May 2014

Borun Pawel, Kubaszewski Lukasz, Banasiewicz Tomasz, Walkowiak Jaroslaw, Skrzypczak-Zielinska Marzena, Kaczmarek-Rys Marta, Plawski Andrzej

Abstract excerpt

Efficient and cost-effective screening for DNA sequence changes, both small mutations and copy number variations (CNVs), is a crucial aspect for routine genetic diagnostics as well as for basic research. In this study we present a development and evaluation of comparative-high resolution melting (C-HRM), a new approach for the simultaneous screening of small DNA changes and gene CNVs. In contrast to other...

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PMID: 24233542
DOI: 10.1007/s00439-013-1393-1
PMCID: PMC3984413

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DMD
APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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