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Article

Deciphering the role of natural variation in age-related protein homeostasis.

BMC biology - 30 Sept 2013

Kaeberlein Matt

Abstract excerpt

Understanding the genetic basis of age-related diseases is a critical step toward developing therapies that promote healthy aging. Numerous genes have been identified that modulate lifespan, but the influence of natural variation in aging has not been well studied. A new report utilizing a transgenic protein aggregation model in Caenorhabditis elegans has provided important tools and insights into the...

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PMID: 24228595
DOI: 10.1186/1741-7007-11-102
PMCID: PMC3849513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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