Article
Genetic variation in neurodegenerative diseases and its accessibility in the model organism Caenorhabditis elegans.
Human genomics - 25 May 2017
Wang Yiru Anning, Kammenga Jan Edward, Harvey Simon Crawford
Abstract excerpt
BACKGROUND: Neurodegenerative diseases (NGDs) such as Alzheimer's and Parkinson's are debilitating and largely untreatable conditions strongly linked to age. The clinical, neuropathological, and genetic components of NGDs indicate that neurodegeneration is a complex trait determined by multiple genes and by the environment. MAIN BODY: The symptoms of NGDs differ among individuals due to their genetic background,...
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