Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanisms of aging-related proteinopathies in Caenorhabditis elegans

7 Oct 2016

Abstract excerpt

Aging is the most important risk factor for human neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. Pathologically, these diseases are characterized by the deposition of specific protein aggregates in neurons and glia, representing the impairment of neuronal proteostasis. However, the mechanism by which aging affects the proteostasis system and promotes protein aggregation remains largely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Genetics, Aging, and Longevity in Model Organisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27713398
DOI: 10.1038/emm.2016.109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanisms of aging-related proteinopathies in Caenorhabditis elegansPMID 27713398Read ↗

Deciphering the role of natural variation in age-related protein homeostasis.Semantic proximity Read ↗

Neurodegenerative disorders: insights from the nematode Caenorhabditis elegans.Semantic proximity Read ↗

Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in <i>C. elegans</i>Semantic proximity Read ↗

Sirtuins and Autophagy in Age-Associated Neurodegenerative Diseases: Lessons from the C. elegans ModelSemantic proximity Read ↗

Genetic screens in Caenorhabditis elegans models for neurodegenerative diseasesSemantic proximity Read ↗

Caenorhabditis elegans Models CountSemantic proximity Read ↗

Studying the mechanisms of neurodegeneration: C. elegans advantages and opportunitiesSemantic proximity Read ↗

Caenorhabditis elegans as a Model System to Study Human Neurodegenerative DisordersSemantic proximity Read ↗

Amyotrophic Lateral Sclerosis Mechanism: Insights from the Caenorhabditis elegans ModelsSemantic proximity Read ↗

Caenorhabditis elegans models of tauopathySemantic proximity Read ↗

C. elegans models of age-associated neurodegenerative diseases: Lessons from transgenic worm models of Alzheimer’s diseaseSemantic proximity Read ↗

Caenorhabditis elegans Models to Investigate the Mechanisms Underlying Tau Toxicity in TauopathiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.