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Article

Genetic factors associated with gemcitabine pharmacokinetics, disposition, and toxicity.

Pharmacogenetics and genomics - 1 Jan 2014

Knights Jonathan, Sato Yasunori, Kaniwa Nahoko, Saito Yoshiro, Ueno Hideki, Ramanathan Murali

Abstract excerpt

AIM: The goal of this work was to investigate the associations of genetic and environmental factors with gemcitabine disposition and toxicity from genomewide data using a novel information theoretic approach. METHODS: We utilized the information theoretic K-way interaction information (KWII) metric to detect gene-gene and gene-environment interactions associated with gemcitabine disposition and...

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Source

Identifiers

PMID: 24225399
DOI: 10.1097/FPC.0000000000000016

Genes

CNTN4
DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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