Article
A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.
Pharmacogenetics and genomics - 1 Apr 2012
Kiyotani Kazuma, Uno Satoko, Mushiroda Taisei, Takahashi Atsushi, Kubo Michiaki, Mitsuhata Naoki, Ina Shinomi, Kihara Chikashi, Kimura Yasutoshi, Yamaue Hiroki, Hirata Koichi, Nakamura Yusuke, Zembutsu Hitoshi
Abstract excerpt
OBJECTIVE: Genetic factors are thought to be one of the causes of individual variability in the adverse reactions observed in cancer patients who received gemcitabine therapy. However, genetic factors determining the risk of adverse reactions of gemcitabine are not fully understood. PATIENTS AND...
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