Article
Identification and analysis of single-nucleotide polymorphisms in the gemcitabine pharmacologic pathway.
The pharmacogenomics journal - 1 Jan 2004
Fukunaga A K, Marsh S, Murry D J, Hurley T D, McLeod H L
Abstract excerpt
Significant variability in the antitumor efficacy and systemic toxicity of gemcitabine has been observed in cancer patients. However, there are currently no tools for prospective identification of patients at risk for untoward events. This study has identified and validated single-nucleotide poly...
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