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Article

Identification and analysis of single-nucleotide polymorphisms in the gemcitabine pharmacologic pathway.

The pharmacogenomics journal - 1 Jan 2004

Fukunaga A K, Marsh S, Murry D J, Hurley T D, McLeod H L

Abstract excerpt

Significant variability in the antitumor efficacy and systemic toxicity of gemcitabine has been observed in cancer patients. However, there are currently no tools for prospective identification of patients at risk for untoward events. This study has identified and validated single-nucleotide polymorphisms (SNP) in genes involved in gemcitabine metabolism and transport. Database mining was conducted to identify...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15224082
DOI: 10.1038/sj.tpj.6500259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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