Article
Distribution of gemcitabine pathway genotypes in ethnic Asians and their association with outcome in non-small cell lung cancer patients.
Lung cancer (Amsterdam, Netherlands) - 1 Jan 2009
Soo Ross A, Wang Ling Zhi, Ng Swee Siang, Chong Pei Yi, Yong Wei Peng, Lee Soo Chin, Liu Jian Jun, Choo Tai Bee, Tham Lai San, Lee How Sung, Goh Boon Cher, Soong Richie
Abstract excerpt
OBJECTIVE: Pharmacogenetics suggests variants of genes involved in gemcitabine pharmacology could be useful markers for predicting inter-ethnic and inter-patient outcomes from treatment with the agent. Here, we have characterized the distribution of variants of genes involved in gemcitabine pharmacology in ethnic Asian populations and their association with non-small cell lung cancer (NSCLC) patient outcome....
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