Article
Selectome update: quality control and computational improvements to a database of positive selection.
Nucleic acids research - 1 Jan 2014
Moretti Sébastien, Laurenczy Balazs, Gharib Walid H, Castella Briséïs, Kuzniar Arnold, Schabauer Hannes, Studer Romain A, Valle Mario, Salamin Nicolas, Stockinger Heinz, Robinson-Rechavi Marc
Abstract excerpt
Selectome (http://selectome.unil.ch/) is a database of positive selection, based on a branch-site likelihood test. This model estimates the number of nonsynonymous substitutions (dN) and synonymous substitutions (dS) to evaluate the variation in selective pressure (dN/dS ratio) over branches and over sites. Since the original release of Selectome, we have benchmarked and implemented a thorough quality control...
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