Article
Fas gene variants in childhood acute lymphoblastic leukemia and association with prognosis.
Pathology oncology research : POR - 1 Apr 2014
Valibeigi Behnaz, Amirghofran Zahra, Golmoghaddam Hossein, Hajihosseini Reza, Kamazani Fatemeh M
Abstract excerpt
Fas molecule is one of the main important molecules involved in apoptotic cell death. Single nucleotide polymorphisms in the promoter of Fas gene at positions -1377G/A and -670 A/G may affect its expression and play an important role in the pathology of leukemia. In the present study the association between these polymorphisms and risk of the development of acute lymphoblastic leukemia (ALL) in children with ALL...
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