Article
Association of the polymorphisms in the Fas/FasL promoter regions with cancer susceptibility: a systematic review and meta-analysis of 52 studies.
PloS one - 1 Jan 2014
Xu Yeqiong, He Bangshun, Li Rui, Pan Yuqin, Gao Tianyi, Deng Qiwen, Sun Huiling, Song Guoqi, Wang Shukui
Abstract excerpt
Fas and its ligand (FasL) play an important role in apoptosis and carcinogenesis. Therefore, the potential association of polymorphisms in the Fas (-670A>G, rs1800682; -1377G>A, rs2234767) and FasL (-844C>T, rs763110) with cancer risk has been widely investigated. However, all the currently available results are not always consistent. In this work, we performed a meta-analysis to further determine whether...
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