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Article

Functional polymorphisms in FAS, FASL and CASP8 genes and risk of childhood acute lymphoblastic leukemia: a case-control study.

Leukemia & lymphoma - 1 Jul 2012

Tong Na, Zhang Limei, Sheng Xiaojing, Wang Meilin, Zhang Zhizhong, Fang Yongjun, Xue Yao, Li Jie, Zhang Zhengdong

Abstract excerpt

Genetic polymorphisms in the promoter regions of FAS, FASL and CASP8 involved in the apoptotic signaling pathway are thought to be associated with susceptibility to cancer. We hypothesized that these functional genetic variants might be associated with the risk of childhood acute lymphoblastic leukemia (ALL). A case-control study in a Chinese population with 361 cases of ALL and 519 controls was performed to...

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Identifiers

PMID: 22211869
DOI: 10.3109/10428194.2011.654117

Genes

FAS
CASP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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