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Article

P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis.

Human molecular genetics - 1 Apr 2014

Sakami Sanae, Kolesnikov Alexander V, Kefalov Vladimir J, Palczewski Krzysztof

Abstract excerpt

Retinal rod photoreceptor cells have double membrane discs located in their outer segments (ROS) that are continuously formed proximally from connecting cilia (CC) and phagocytized distally by the retinal pigmented epithelium. The major component of these rod discs, the light-sensitive visual pigment rhodopsin (Rho), consists of an opsin protein linked to 11-cis-retinal. The P23H mutation of rod opsin (P23H...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24214395
DOI: 10.1093/hmg/ddt561
PMCID: PMC3943518

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ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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