Article
Mutant rhodopsin transgene expression on a null background.
Investigative ophthalmology & visual science - 1 Mar 2001
Frederick J M, Krasnoperova N V, Hoffmann K, Church-Kopish J, Rüther K, Howes K, Lem J, Baehr W
Abstract excerpt
PURPOSE: To study mechanisms leading to photoreceptor degeneration in mouse models for autosomal dominant retinitis pigmentosa (adRP) based on the rhodopsin P23H mutation. METHODS: Mice of a transgenic line expressing a rhodopsin triple mutant, V20G, P23H, and P27L (GHL), were mated with rhodopsi...
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