Article
High-resolution array CGH profiling identifies Na/K transporting ATPase interacting 2 (NKAIN2) as a predisposing candidate gene in neuroblastoma.
PloS one - 1 Jan 2013
Romania Paolo, Castellano Aurora, Surace Cecilia, Citti Arianna, De Ioris Maria Antonietta, Sirleto Pietro, De Mariano Marilena, Longo Luca, Boldrini Renata, Angioni Adriano, Locatelli Franco, Fruci Doriana
Abstract excerpt
Neuroblastoma (NB), the most common solid cancer in early childhood, usually occurs sporadically but also its familial occurance is known in 1-2% of NB patients. Germline mutations in the ALK and PHOX2B genes have been found in a subset of familial NBs. However, because some individuals harbourin...
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