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Article

Genetic predisposition and chromosome instability in neuroblastoma.

Cancer metastasis reviews - 1 Mar 2020

Tonini Gian Paolo, Capasso Mario

Abstract excerpt

Neuroblastoma (NB) is a pediatric tumor of embryonic origin. About 1-2% of all NBs are familial cases, and genetic predisposition is suspected for the remaining cases. During the last decade, genome-wide association studies (GWAS) and high-throughput sequencing approaches have been used to identify associations among common and rare genetic variants and NB risk. Substantial data has been produced by large patient...

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PMID: 31927719
DOI: 10.1007/s10555-020-09843-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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