Identification of a novel recurrent 1q42.2‐1qter deletion in high risk <i>MYCN</i> single copy 11q deleted neuroblastomas

Abstract excerpt

Neuroblastoma is an aggressive embryonal tumor that accounts for ∼15% of childhood cancer deaths. Hitherto, despite the availability of comprehensive genomic data on DNA copy number changes in neuroblastoma, relatively little is known about the genes driving neuroblastoma tumorigenesis. In this study, high resolution array comparative genome hybridization (CGH) was performed on 188 primary neuroblastoma tumors...

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