Article
Evolution of recombination due to random drift.
Genetics - 1 Apr 2005
Barton N H, Otto Sarah P
Abstract excerpt
In finite populations subject to selection, genetic drift generates negative linkage disequilibrium, on average, even if selection acts independently (i.e., multiplicatively) upon all loci. Negative disequilibrium reduces the variance in fitness and hence, by Fisher's (1930) fundamental theorem, slows the rate of increase in mean fitness. Modifiers that increase recombination eliminate the negative disequilibria...
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