Article
Coalescence and genetic diversity in sexual populations under selection.
Proceedings of the National Academy of Sciences of the United States of America - 24 Sept 2013
Neher Richard A, Kessinger Taylor A, Shraiman Boris I
Abstract excerpt
In sexual populations, selection operates neither on the whole genome, which is repeatedly taken apart and reassembled by recombination, nor on individual alleles that are tightly linked to the chromosomal neighborhood. The resulting interference between linked alleles reduces the efficiency of selection and distorts patterns of genetic diversity. Inference of evolutionary history from diversity shaped by linked...
Topics
- Adaptation, Physiological
- Genealogy and Heraldry
- Genetic Fitness
- Genetic Loci
- Genetic Variation
- Genetics, Population
- Humans
- Linkage Disequilibrium
- Models, Genetic
- Mutation
- Recombination, Genetic