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Article

Using information interaction to discover epistatic effects in complex diseases.

PloS one - 1 Jan 2013

Anunciação Orlando, Vinga Susana, Oliveira Arlindo L

Abstract excerpt

It is widely agreed that complex diseases are typically caused by the joint effects of multiple instead of a single genetic variation. These genetic variations may show stronger effects when considered together than when considered individually, a phenomenon known as epistasis or multilocus interaction. In this work, we explore the applicability of information interaction to discover pairwise epistatic effects...

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Identifiers

PMID: 24194833
DOI: 10.1371/journal.pone.0076300
PMCID: PMC3806769

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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