The *1244 A>G polymorphism of MyD88 (rs7744) is closely associated with susceptibility to ulcerative colitis.

doi:10.3892/mmr.2013.1769

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Article

The *1244 A>G polymorphism of MyD88 (rs7744) is closely associated with susceptibility to ulcerative colitis.

Molecular medicine reports - 1 Jan 2014

Matsunaga Kazuhiro, Tahara Tomomitsu, Shiroeda Hisakazu, Otsuka Toshimi, Nakamura Masakatsu, Shimasaki Takeo, Toshikuni Nobuyuki, Kawada Natsuko, Shibata Tomoyuki, Arisawa Tomiyasu

Abstract excerpt

Toll‑like receptor activation intitially recruits the myeloid differentiation primary response gene (88) (MyD88) protein. A polymorphism *1244 A>G (rs7744) in the 3'‑untranslated region of MyD88 has been identified. In the present study, the association of this polymorphism with ulcerative colitis (UC) was investigated. The population studied comprised 922 individuals, including patients with UC (UC cases) and...

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PMID: 24189845
DOI: 10.3892/mmr.2013.1769

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