Article
MICB0106 gene polymorphism is associated with ulcerative colitis in central China.
International journal of colorectal disease - 1 Feb 2010
Li Yi, Xia Bing, Lü Min, Ge Liuqing, Zhang Xiaolian
Abstract excerpt
BACKGROUND: The highly polymorphic nonclassical MHC class I chain-related genes A and B (MICA and MICB) encode stress-inducible glycoproteins expressed on various epithelial cells including intestinal epithelial cells. MICA and MICB gene polymorphisms and expressions are associated with autoimmune diseases but not known in ulcerative colitis (UC). AIMS: To investigate the association of MICB exon 2-4...
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