Article
Association between toll-like receptors/CD14 gene polymorphisms and inflammatory bowel disease in Korean population.
Journal of Korean medical science - 1 Jan 2012
Kim Eun Jung, Chung Woo Chul, Lee Kang-Moon, Paik Chang Nyol, Jung Sung Hoon, Lee Bo In, Chae Hiun Suk, Choi Kyu Yong
Abstract excerpt
The innate immune response in patients who develop inflammatory bowel disease (IBD) may be abnormal. However, the exact role of Toll-like receptors (TLRs) / CD14 gene in the pathogenesis of IBD has not been fully elucidated. We aimed to investigate the association between polymorphisms of TLR1, 2, 4, 6, and CD14 gene and susceptibility to IBD in Korean population. A total 144 patients of IBD (99 patients with...
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