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Article

Host genetic factors, related to inflammatory response, influence the CpG island methylation status in colonic mucosa in ulcerative colitis.

Anticancer research - 1 Mar 2011

Tahara Tomomitsu, Shibata Tomoyuki, Nakamura Masakatsu, Okubo Masaaki, Yamashita Hiromi, Yoshioka Daisuke, Yonemura Joh, Kmiya Yoshio, Ishizuka Takamitsu, Fujita Hiroshi, Nagasaka Mitsuo, Yamada Hideto, Hirata Ichiro, Arisawa Tomiyasu

Abstract excerpt

BACKGROUND: CpG island hypermethylation (CIHM) in gene promoter is frequently observed in the colonic mucosa in ulcerative colitis (UC), and is strongly involved in UC-associated colorectal carcinogenesis (CRC). The influence of common single nucleotide polymorphisms (SNPs) related to inflammatory immune response on the individual susceptibility to CIHM status in the non-neoplastic rectal mucosa in UC patients...

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Share to Colitis, Ulcerative
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to MBL2 gene

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Source

Identifiers

PMID: 21498716

Genes

MBL2
CDH1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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