Article
Functional MICA-129 polymorphism and serum levels of soluble MICA are correlated with ulcerative colitis in Chinese patients.
Journal of gastroenterology and hepatology - 1 Mar 2011
Zhao Jie, Jiang Yi, Lei Yuan, Zou Kaifang, Wang Changgao, Huang Sha, Yi Fengming, Xia Bing
Abstract excerpt
BACKGROUND AND AIM: The aim of the present study was to evaluate the contribution of the dimorphism (MICA-129 val and met) to the genetic susceptibility and functions of ulcerative colitis (UC) in patients in central China. METHODS: Genotyping of MICA-129 was performed in 272 consecutive UC patients and 560 age- and sex-matched healthy individuals by using a polymerase chain reaction-sequencing based typing...
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