Glucagon gene polymorphism modifies the effects of smoking and physical activity on risk of type 2 diabetes mellitus in Han Chinese.

doi:10.1016/j.gene.2013.09.121

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Glucagon gene polymorphism modifies the effects of smoking and physical activity on risk of type 2 diabetes mellitus in Han Chinese.

Gene - 25 Jan 2014

Li Linlin, Gao Kaiping, Zhao Jingzhi, Feng Tianping, Yin Lei, Wang Jinjin, Wang Chongjian, Li Chunyang, Wang Yan, Wang Qian, Zhai Yujia, You Haifei, Ren Yongcheng, Wang Bingyuan, Hu Dongsheng

Abstract excerpt

Few genome-wide association studies have considered interactions between multiple genetic variants and environmental factors associated with disease. The interaction was examined between a glucagon gene (GCG) polymorphism and smoking, alcohol consumption and physical activity and the association with risk of type 2 diabetes mellitus (T2DM) in a case-control study of Chinese Han subjects. The rs12104705...

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PMID: 24185078
DOI: 10.1016/j.gene.2013.09.121

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