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[Screening of variation in the promoter of PPARGC1A gene and study of its association with the risk of type 2 diabetes in ethnic Hans from Beijing].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2014

Sun Liang, Wang Songlan, Qu Yanchun, Sun Hong, Wang Xiaoxia, Shi Xiaohong, Zhu Xiaoquan, Tang Lei, Yang Ze

Abstract excerpt

OBJECTIVE: To study the baseline distribution of polymorphisms in the promoter of peroxisome proliferators activated receptor co-activator 1 (PPARGC1A) gene in ethnic Hans from Beijing, and to assess their association with type 2 diabetes (T2DM). METHODS: A 2-stage study was designed. Firstly, the promoter region of PPAGC1A gene was screened with PCRRFLP in a small population (n=216, T2DM/control: 104/112), which...

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Identifiers

PMID: 24928019
DOI: 10.3760/cma.j.issn.1003-9406.2014.03.021

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