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Interactions between genetic polymorphisms of glucose metabolizing genes and smoking and alcohol consumption in the risk of type 2 diabetes mellitus.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme - 1 Dec 2017

Gao Kaiping, Ren Yongcheng, Wang Jinjin, Liu Zichen, Li Jianna, Li Linlin, Wang Bingyuan, Li Hong, Wang Yaxi, Cao Yunkai, Ohno Kinji, Zhai Rihong, Liang Zhen

Abstract excerpt

The impact of gene-environment interaction on diabetes remains largely unknown. We aimed to investigate if interaction between glucose metabolizing genes and lifestyle factors is associated with type 2 diabetes mellitus (T2DM). Interactions between genotypes of 4 glucose metabolizing genes (MTNR1B, KCNQ1, KLF14, and GCKR) and lifestyle factors were estimated in 722 T2DM patients and 759 controls, using multiple...

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Alcohol Drinking
Asian People
Diabetes Mellitus, Type 2
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

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Identifiers

PMID: 28806535
DOI: 10.1139/apnm-2017-0232

Genes

KCNQ1
GCKR
KLF14

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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