Article
PPARGC1A rs3736265 G>A polymorphism is associated with decreased risk of type 2 diabetes mellitus and fasting plasma glucose level.
Oncotarget - 6 Jun 2017
Zhu Li, Huang Qiuyu, Xie Zhiqiang, Kang Mingqiang, Ding Hao, Chen Boyang, Chen Yu, Liu Chao, Wang Yafeng, Tang Weifeng
Abstract excerpt
It has been reported that peroxisome proliferator-activated receptor gamma (PPARG) and peroxisome proliferator-activated receptor gamma co-activator 1 (PPARGC1) family (e.g. PPARGC1A and PPARGC1B) are key agents in the development and pathophysiology of type 2 diabetes mellitus (T2DM). In this study, we designed a case-control study and selected PPARG rs1801282 C>G, PPARG rs3856806 C>T, PPARGC1A rs8192678 C>T,...
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