Article
Glucose levels and genetic variants across transcriptional pathways: interaction effects with BMI.
International journal of obesity (2005) - 1 May 2010
Povel C M, Feskens E J M, Imholz S, Blaak E E, Boer J M A, Dollé M E T
Abstract excerpt
OBJECTIVE: Much of the genetic variation in glucose levels remains to be discovered. Especially, research on gene-environment interactions is scarce. Overweight is one of the main risk factors for hyperglycemia. As transcriptional regulation is important for both weight maintenance and glucose control, we analyzed 353 single nucleotide polymorphisms (SNPs), occurring in transcriptional pathways of glucose and...
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