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Adiponectin and peroxisome proliferator-activated receptor-γ gene polymorphisms and gene-gene interactions with type 2 diabetes.

Life sciences - 7 Mar 2014

Ye Enling, Yang Hong, Chen Liangmiao, Chen Qingshou, Sun Mengli, Lin Zhenzhen, Yu Lechu, Peng Mengmeng, Zhang Chi, Lu Xuemian

Abstract excerpt

AIMS: To investigate whether gene polymorphisms of both adiponectin and peroxisome proliferator-activated receptor gamma (PPARγ) influence type 2 diabetes mellitus (T2DM) respectively in the Han people of the Wenzhou region of China and whether the interaction of gene polymorphism between adiponectin and PPARγ influences T2DM in the same subjects. MAIN METHODS: This study included 198 patients with T2DM and 255...

Topics

Adiponectin
China
Diabetes Mellitus, Type 2
Epistasis, Genetic
Female
Genetic Predisposition to Disease
Humans
Male
Middle Aged
PPAR gamma
Polymorphism, Genetic

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PMID: 24440313
DOI: 10.1016/j.lfs.2013.12.232

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