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Differences in EGFR and KRAS mutation spectra in lung adenocarcinoma of never and heavy smokers

29 Aug 2013

Abstract excerpt

Epidermal growth factor receptor (EGFR) mutations are common in lung adenocarcinomas of never smokers, while KRAS mutations are more frequent among heavy smokers. Different clinicopathological and biological characteristics may, therefore, exist in lung adenocarcinoma according to smoking status. In the present study, a retrospective review was performed using 521 patients with surgically resected lung...

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PMID: 24179496
DOI: 10.3892/ol.2013.1551

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