Article
Divergent epidermal growth factor receptor mutation patterns between smokers and non-smokers with lung adenocarcinoma.
Lung cancer (Amsterdam, Netherlands) - 1 Dec 2015
Tseng Jeng-Sen, Wang Chih-Liang, Yang Tsung-Ying, Chen Chih-Yi, Yang Cheng-Ta, Chen Kun-Chieh, Hsu Kuo-Hsuan, Tsai Chi-Ren, Chang Gee-Chen
Abstract excerpt
INTRODUCTION: Smoking status is an important determinant of the prevalence of epidermal growth factor receptor (EGFR) mutations in lung cancer patients. However, it is unclear whether smoking status could also influence the spectrum of EGFR mutations. METHODS: We enrolled patients with lung adenocarcinoma from three medical centers in Taiwan. EGFR mutations were assessed by Sanger direct sequencing. The objective...
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