Lung cancer mutation profile of EGFR, ALK, and KRAS: Meta-analysis and comparison of never and ever smokers.

doi:10.1016/j.lungcan.2016.10.010

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Article

Lung cancer mutation profile of EGFR, ALK, and KRAS: Meta-analysis and comparison of never and ever smokers.

Lung cancer (Amsterdam, Netherlands) - 1 Dec 2016

Chapman Aaron M, Sun Kathie Y, Ruestow Peter, Cowan Dallas M, Madl Amy K

Abstract excerpt

Lung cancer is the leading cause of cancer-related mortality. While the majority of lung cancers are associated with tobacco smoke, approximately 10-15% of U.S. lung cancers occur in never smokers. Evidence suggests that lung cancer in never smokers appears to be a distinct disease caused by driv...

Topics

Anaplastic Lymphoma Kinase
ErbB Receptors
Humans
Lung Neoplasms
Mutation
Prevalence
Proto-Oncogene Proteins p21(ras)
Receptor Protein-Tyrosine Kinases
Smoking

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