Article
Driver mutations among never smoking female lung cancer tissues in China identify unique EGFR and KRAS mutation pattern associated with household coal burning.
Respiratory medicine - 1 Nov 2013
Hosgood H Dean, Pao William, Rothman Nathaniel, Hu Wei, Pan Yumei Helen, Kuchinsky Kyle, Jones Kirk D, Xu Jun, Vermeulen Roel, Simko Jeff, Lan Qing
Abstract excerpt
Lung cancer in never smokers, which has been partially attributed to household solid fuel use (i.e., coal), is etiologically and clinically different from lung cancer attributed to tobacco smoking. To explore the spectrum of driver mutations among lung cancer tissues from never smokers, specifically in a population where high lung cancer rates have been attributed to indoor air pollution from domestic coal use,...
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