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Article

Origin and differential selection of allelic variation at TAS2R16 associated with salicin bitter taste sensitivity in Africa.

Molecular biology and evolution - 1 Feb 2014

Campbell Michael C, Ranciaro Alessia, Zinshteyn Daniel, Rawlings-Goss Renata, Hirbo Jibril, Thompson Simon, Woldemeskel Dawit, Froment Alain, Rucker Joseph B, Omar Sabah A, Bodo Jean-Marie, Nyambo Thomas, Belay Gurja, Drayna Dennis, Breslin Paul A S, Tishkoff Sarah A

Abstract excerpt

Bitter taste perception influences human nutrition and health, and the genetic variation underlying this trait may play a role in disease susceptibility. To better understand the genetic architecture and patterns of phenotypic variability of bitter taste perception, we sequenced a 996 bp region, encompassing the coding exon of TAS2R16, a bitter taste receptor gene, in 595 individuals from 74 African populations...

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Identifiers

PMID: 24177185
DOI: 10.1093/molbev/mst211
PMCID: PMC3907056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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