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Article

Genetic variation in taste receptor pseudogenes provides evidence for a dynamic role in human evolution.

BMC evolutionary biology - 13 Sept 2014

Risso Davide, Tofanelli Sergio, Morini Gabriella, Luiselli Donata, Drayna Dennis

Abstract excerpt

BACKGROUND: Human bitter taste receptors are encoded by a gene family consisting of 25 functional TAS2R loci. In addition, humans carry 11 TAS2R pseudogenes, some of which display evidence for substantial diversification among species, showing lineage-specific loss of function. Since bitter taste is thought to help prevent the intake of toxic substances, diversity at TAS2R genes could reflect the action of...

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Identifiers

PMID: 25216916
DOI: 10.1186/s12862-014-0198-8
PMCID: PMC4172856

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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