Article
Evolution of functionally diverse alleles associated with PTC bitter taste sensitivity in Africa.
Molecular biology and evolution - 1 Apr 2012
Campbell Michael C, Ranciaro Alessia, Froment Alain, Hirbo Jibril, Omar Sabah, Bodo Jean-Marie, Nyambo Thomas, Lema Godfrey, Zinshteyn Daniel, Drayna Dennis, Breslin Paul A S, Tishkoff Sarah A
Abstract excerpt
Although human bitter taste perception is hypothesized to be a dietary adaptation, little is known about genetic signatures of selection and patterns of bitter taste perception variability in ethnically diverse populations with different diets, particularly from Africa. To better understand the genetic basis and evolutionary history of bitter taste sensitivity, we sequenced a 2,975 bp region encompassing TAS2R38,...
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