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Article

Genes from the TAS1R and TAS2R Families of Taste Receptors: Looking for Signatures of Their Adaptive Role in Human Evolution.

Genome biology and evolution - 1 Apr 2018

Valente Cristina, Alvarez Luis, Marques Patrícia Isabel, Gusmão Leonor, Amorim António, Seixas Susana, João Prata Maria

Abstract excerpt

Taste perception is crucial in monitoring food intake and, hence, is thought to play a significant role in human evolution. To gain insights into possible adaptive signatures in genes encoding bitter, sweet, and umami taste receptors, we surveyed the available sequence variation data from the 1000 Genomes Project Phase 3 for TAS1R (TAS1R1-3) and TAS2R (TAS2R16 and TAS2R38) families. Our study demonstrated that...

Topics

Africa
Alleles
Evolution, Molecular
Genetic Variation
Haplotypes
Humans
Polymorphism, Single Nucleotide
Receptors, G-Protein-Coupled
Taste
Taste Buds

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29635333
DOI: 10.1093/gbe/evy071
PMCID: PMC5905477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-29635333-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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