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Article

Stability of unfrozen whole blood DNA for remote genotypic analysis of HIV-1 coreceptor tropism.

BMC infectious diseases - 30 Oct 2013

Meini Genny, Materazzi Angelo, Saladini Francesco, Rosi Andrea, Vicenti Ilaria, Mancini Michele, Pirazzoli Antonella, Caudai Cinzia, Zazzi Maurizio

Abstract excerpt

BACKGROUND: Maraviroc is an HIV-1 coreceptor antagonist that has shown good efficacy and tolerability in treatment-naive and treatment-experienced patients harboring CCR5-tropic virus. The use of Maraviroc in treatment simplification in patients with suppressed plasma HIV-1 RNA requires analysis of HIV-1 DNA. Coreceptor tropism testing is often performed remotely at reference laboratories. In this study paired...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Envelope Protein gp120

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Source

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Identifiers

PMID: 24172636
DOI: 10.1186/1471-2334-13-508
PMCID: PMC3819463

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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