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Article

Differential requirement for Dab2 in the development of embryonic and extra-embryonic tissues.

BMC developmental biology - 29 Oct 2013

Moore Robert, Cai Kathy Qi, Tao Wensi, Smith Elizabeth R, Xu Xiang-Xi

Abstract excerpt

BACKGROUND: Disabled-2 (Dab2) is an endocytic adaptor protein involved in clathrin-mediated endocytosis and cargo trafficking. Since its expression is lost in several cancer types, Dab2 has been suggested to be a tumor suppressor. In vitro studies indicate that Dab2 establishes epithelial cell polarity and organization by directing endocytic trafficking of membrane glycoproteins. Dab2 also modulates cellular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24168030
DOI: 10.1186/1471-213X-13-39
PMCID: PMC3924344

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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